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标题:Advances in molecular classification and precision oncology in hepatocellular carcinoma
时间:2021-04-08 10:48:52
DOI:10.1016/j.jhep.2019.08.017
大小:1910 kb
页数:16 PAGES
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目录:
  • Mechanisms of malignant transformation
    • On cirrhosis
    • On non-cirrhotic liver
  • Molecular classification of hepatocellular carcinoma
    • Mutational, transcriptomic and epigenetic landscape
    • Integrative analysis and correlation with clinical and pathological features
  • Tumour progression and tumour heterogeneity
    • Tumour aggressiveness and mechanisms of progression
    • Tumour heterogeneity in HCC
  • Precision oncology in HCC
    • Biomarkers of response to tyrosine kinase inhibitors
    • Biomarkers of response to immunotherapy
    • How to model response to target therapy?
    • New biomarkers
  • Conclusion
    • Abbreviations
  • Financial support
  • Conflicts of interests
  • Author contributions
  • Acknowledgment
  • Supplementary data
  • References
    • Author names in bold designate shared co-first authorship

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