The Functional Gastrointestinal Disorders and the Rome III Process

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标题：	The Functional Gastrointestinal Disorders and the Rome III Process
时间：	2021-02-23 15:39:18
DOI：	10.1053/j.gastro.2006.03.008
大小：	356 kb
页数：	15 PAGES
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The Functional Gastrointestinal Disorders and the Rome III Process
- The Rome III Classification System FGIDs
- Scientific Observations on the Pathophysiology of Functional GI Disorders
  - Genetic Predispositions
  - Early Family Environment
  - Psychosocial Factors
  - Abnormal Motility
  - Visceral Hypersensitivity
  - Inflammation
  - Bacterial Flora
  - Brain-Gut Interactions via the CNS-ENS
    - Bidirectional “hardwiring” of brain-gut axis
    - Stress and postinfectious FGID
    - Brain imaging
    - Brain-gut peptides
- An Approach to the Care of Patients With Functional GI Disorders
  - The Therapeutic Relationship
    - Mild symptoms
    - Moderate symptoms
    - Severe symptoms
- The Rome Committees and Criteria Development
  - Rationale for Symptom-Based Diagnostic Criteria
    - Site-specific differences
    - Symptoms resulting from multiple in.uencing factors
    - Epidemiologic data
    - Treatment implications
    - Need for diagnostic standards in clinical care and research
  - Qualifications for the Use of Symptom- Based Criteria
    - Other diseases may coexist that need to be excluded
    - Symptoms may overlap with other functional GI disorders
    - Symptoms must have begun 6 months prior to diagnosis and be active for 3 months
    - Diagnostic categories do not include psychosocial criteria
    - Criteria are determined by clinical consensus and existing evidence
  - The Rome Committee Process
  - Changes Made in Rome III
- Concluding Comments
- Acknowledgment
- References

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