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标题:Myricetin derivative-rich fraction from Syzygium malaccense prevents high-fat diet-induced obesity, glucose intolerance and oxidative stress in C57BL/6J mice
时间:2021-02-22 18:07:21
DOI:10.1080/13813455.2020.1808019
大小:2713 kb
页数:14 PAGES
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目录:
  • Abstract
    • Introduction
    • Materials and methods
      • Materials
      • Animal model and ethic statement
      • Isolation of myricetin derivative- rich fraction (MD)
      • Experimental design
      • Body weight, average caloric intake, Lee index and blood glucose level measurements
      • Sample collection and analytical methods
      • Biochemical analysis
        • Oral glucose tolerance test (OGTT)
        • Insulin sensitivity test and HOMA-IR
        • Estimation of serum biochemistry profiles
      • Assessment of oxidative stress biomarkers
        • Advanced oxidation protein products (AOPP)
        • Lipid hydroperoxide (LHP)
        • Thiobarbituric acid reactive substances (TBARS)
      • Assessment of antioxidant activity
        • Reduced glutathione (GSH)
        • Ferric reducing antioxidant power (FRAP)
        • Trolox equivalent antioxidant capacity (TEAC)
      • Histopathological examination
      • Statistical analysis
    • Results
      • Body weight, net body weight change, average caloric intake, and lee index
      • Fasting blood glucose level (FBGL)
      • Oral glucose tolerance test (OGTT)
      • Insulin level and HOMA-IR
      • Serum biochemical tests
      • Histopathological analysis
      • Oxidative stress biomarkers and antioxidant measurement
        • Urinary oxidative stress biomarkers and antioxidant measurement
        • Tissue homogenates oxidative indices and antioxidant measurement
    • Discussion
    • Conclusion
    • Disclosure statement
    • References

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