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标题:Overexpression of PARPBP Correlates with Tumor Progression and Poor Prognosis in Hepatocellular Carcinoma
时间:2021-02-20 22:36:30
DOI:10.1007/s10620-019-05608-4
PMID:30949905
大小:5192 kb
页数:16 PAGES
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目录:
  • Overexpression of PARPBP Correlates with Tumor Progression and Poor Prognosis in Hepatocellular Carcinoma
    • Abstract
      • Background
      • Objective
      • Methods
      • Results
      • Conclusion
    • Introduction
    • Materials and Methods
      • Data Mining in the Cancer Genome Atlas (TCGA) Database
      • Data Mining in the Human Protein Atlas (HPA) Database
      • Regulatory miRNAs of PARPBP Prediction
      • Gene Set Enrichment Analysis (GSEA)
      • Statistical Analyses
    • Results
      • PARPBP Was Upregulated in HCC Tissues Compared with Normal Liver Tissues
      • PARPBP Overexpression Correlated with Tumor Progression in HCC
      • PARPBP Overexpression Independently Predicted Poor OS and RFS in HCC
      • Validation of the Prognostic Value of PARPBP in HCC Based on Nomograms
      • DNA Copy Gain and miR-139-5p Downregulation Contributed to PARPBP Upregulation in HCC
      • Gene Set Enrichment Analysis
    • Discussion
    • References

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