在线客服: 点击这里给我发消息  新用户使用步骤:会员注册→充值→重新登入→进入资源
标题:Virus-Mediated Genome Editing via Homology-Directed Repair in Mitotic and Postmitotic Cells in Mammalian Brain
时间:2021-01-13 21:55:12
DOI:10.1016/j.neuron.2017.10.004
大小:8849 kb
页数:21 PAGES
下载: 点击下载
预览:

浏览器不支持嵌入PDF阅读,打开新页面在线阅读

目录:
  • Virus-Mediated Genome Editing via Homology-Directed Repair in Mitotic and Postmitotic Cells in Mammalian Brain
    • Introduction
    • Results
      • HDR-Mediated Genome Editing in the Embryonic Brain
      • HDR-Mediated Genome Editing in Distinct Cell-Types in the Brain
      • HDR-Mediated Genome Editing in Postmitotic Neurons
      • Dual AAV System for HDR-Mediated Genome Editing
      • HDR-Mediated Genome Editing in the Adult Brain In Vivo
      • HDR-Mediated Genome Editing in Aged, Disease-Model Mice
    • Discussion
    • Supplemental Information
    • Author Contributions
    • Acknowledgments
    • References
    • STAR★Methods
      • Key Resources Table
      • Contact for Reagent and Resource Sharing
      • Experimental Model and Subject Details
        • Mice and Rats
        • Primary dissociated cultures
        • Organotypic slice cultures
      • Method Details
        • DNA constructs
        • Genomic PCR and DNA sequencing
        • AAV vector production
        • Viral transduction into cultures in vitro
        • Intraventricular viral injection
        • Stereotaxic viral injection
        • Histology
      • Quantification and Statistical Analysis

本页内容由网络收集而来,版权归原创者所有,如有侵权请及时联系