标题: | Resveratrol Protects SAMP8 Brain Under Metabolic Stress: Focus on Mitochondrial Function and Wnt Pathway |
时间: | 2021-01-11 20:10:23 |
DOI: | 10.1007/s12035-016-9770-0 |
PMID: | 26873850 |
大小: | 1598 kb |
页数: | 17 PAGES |
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目录:
- Resveratrol Protects SAMP8 Brain Under Metabolic Stress: Focus on Mitochondrial Function and Wnt Pathway
- Abstract
- Introduction
- Methods
- Animals
- Glucose Curve
- Novel Object Recognition Test
- Morris Water Maze Test
- Elevated Plus Maze Test
- Open-Field Test
- Three-Chamber Socializing and Social Novelty Test
- Brain Isolation and Western Blot Analysis
- Brain Processing for Ultrastructural Observation on Transmission Electron Microscopy
- RNA Extraction and Gene Expression Determination
- Statistical Analysis
- Results
- Metabolic Changes Induced by High-Fat Diet and Resveratrol: Glucose Tolerance Tests
- Behavioral and Psycoemotional Results
- High-Fat Diet Induced Changes in Oxidative Markers, Mitochondrial Function, and Wnt Pathway: Effects of Resveratrol
- Participation of Wnt Pathway in the Resveratrol Effect After Metabolic Stress Due to High-Fat Diet
- Discussion
- References
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