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标题:Linked CD4 T Cell Help: Broadening Immune Attack Against Cancer by Vaccination
时间:2020-11-22 20:53:56
DOI:10.1007/82_2016_500
大小:655 kb
页数:22 PAGES
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目录:
  • 500 Linked CD4 T Cell Help: Broadening Immune Attack Against Cancer by Vaccination
    • Abstract
    • 1 Introduction
      • 1.1 Tolerogenic Pressure
        • 1.1.1 T Cell Immunity
        • 1.1.2 B Cell Immunity
      • 1.2 Choice of Target Antigen: Specific, Neoantigens and Shared Antigens
      • 1.3 Activation of Relevant Immune Anticancer Mechanisms
    • 2 Targeting Cancer with Vaccination
      • 2.1 DNA Vaccines
      • 2.2 Fragment C of Tetanus Toxin in Fusion DNA Vaccines
      • 2.3 The p.DOM-Epitope Design to Induce CTL Responses
      • 2.4 Clinical Experience with the p.Dom-Epitope Design
        • 2.4.1 Induction of Immune Responses
        • 2.4.2 Understanding the Immunodominance Following p.DOM-Epitope Vaccine Delivery to Patients
      • 2.5 Preexisting Immunity to TT Immunity and Performance of Vaccines Containing TT-Derived Fragments
      • 2.6 Novel Vaccination Approaches Based on FrC Linked T Cell Help
      • 2.7 mRNA Vaccines
      • 2.8 Plant Viral Particles: A Novel Platform for Induction of Immunity Against Cancer
    • 3 Concluding Remarks
    • References

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