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标题:MIF family proteins in genitourinary cancer: tumorigenic roles and therapeutic potential
时间:2020-11-22 11:09:43
DOI:10.1038/s41585-019-0171-9
大小:1513 kb
页数:12 PAGES
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目录:
  • MIF family proteins in genitourinary cancer: tumorigenic roles and therapeutic potential
    • MIF as a potential regulator of immunotherapy
    • MIF signalling mechanisms
      • CD74: a putative MIF receptor.
      • MIF co-​receptors and other mechanisms of action.
      • d-​Dopachrome tautomerase — another MIF family member.
      • Therapeutic inhibition of MIF–CD74 and DDT–CD74 interactions
    • MIF in genitourinary malignancy
      • Prostate cancer.
      • Bladder cancer.
      • Renal cancer.
    • Conclusions
    • Acknowledgements
    • Fig. 1 MIF signalling in cancer cells.
    • Fig. 2 MIF in the microenvironment.
    • Table 1 Common inhibitors of MIF.
    • Table 2 Expression profiles of MIF superfamily members in genitourinary tumours.
    • Table 3 In vivo evidence for therapeutic targeting of MIF.

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