在线客服: 点击这里给我发消息  新用户使用步骤:会员注册→充值→重新登入→进入资源
时间:2020-10-28 16:29:25
DOI:10.1016/j.cell.2013.05.012
PMID:23706738
大小:2584 kb
页数:13 PAGES
下载: 点击下载
预览:

浏览器不支持嵌入PDF阅读,打开新页面在线阅读

目录:
  • Gene Expression Is Circular: Factors for mRNA Degradation Also Foster mRNA Synthesis
    • Introduction
    • Results
      • Steady State mRNA Levels Are Highly Robust to Perturbations in mRNA Decay
      • Disruption of Xrn1p Compromises Transcription of Most Genes
      • Transcriptional Induction Is Dependent on mRNA Decay Factors
      • Xrn1p Affects Pol II Occupancy on TEF4 Gene
      • Various mRNA Decay Factors Shuttle between the Cytoplasm and the Nucleus in a Manner Dependent on Proper mRNA Decay
      • Decay Factors Associate with Chromatin and Stimulate Transcription Initiation
      • Decay Factors Affect Transcription Elongation
      • Transcription Is Linked to mRNA Decay
      • Discussion
      • Decay Factors Play a Direct Role in Transcription
      • Xrn1p Functions Also in Transcription Elongation
      • Decay Factors Might Function in Transcription as a Complex or Subcomplexes
      • The Linkage between mRNA Decay, Import of Decay Factors and Transcription
      • Other Possible Mechanisms
      • Gene Expression Is Circular
    • Experimental Procedures
      • Yeast Strains and Plasmids
      • Yeast Cultures
      • Analysis of Steady State mRNA Level, mRNA Half-Life, and Transcription Induction/Repression
      • Fluorescence Microscopy
      • Fluorescent In Situ Hybridization
      • Genomic Run-On, 3′/5′ Ratio Analysis, Determining HLs and RNA pol II ChIP on Chip Experiments
      • Chromatin Immunoprecipitation
      • Statistical Analysis
    • Accessions Numbers
    • Supplemental Information
    • Acknowledgments
    • References

本页内容由网络收集而来,版权归原创者所有,如有侵权请及时联系