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标题:Effect of artesunate and relation with TGF-β1 and SMAD3 signaling on experimental hypertrophic scar model in rabbit ear
时间:2020-10-27 09:55:09
DOI:10.1007/s00403-019-01960-7
大小:8363 kb
页数:13 PAGES
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目录:
  • Effect of artesunate and relation with TGF-β1 and SMAD3 signaling on experimental hypertrophic scar model in rabbit ear
    • Abstract
    • Introduction
    • Materials and methods
      • Preparation of drugs and chemicals
        • Preparation of paste for a matrix group
        • Preparation of ART cream with different concentrations
      • Animal research and therapy
      • H&E and determination of Scar Elevation Index
      • Van Gieson staining
      • Immunohistochemical analysis
      • Western blot analyses
      • Statistical analysis
    • Results
      • Effect of ART cream on hypertrophic scars in rabbit’s ear
      • H&E and VG staining findings
      • Hypertrophic Index (HI), fibroblast number density (NA), and the surface density of collagen fibers (AA)
      • Effect of ART on TGF-β1 protein expression
      • Effect of ART on SMAD 3 protein expression
      • Western blot detection of TGF-β1 protein expression and SMAD 3 protein expression
    • Discussion
    • References

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