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标题:Identification of dysregulated genes and pathways of different brain regions in Alzheimer’s disease
时间:2020-10-25 21:37:22
DOI:10.1080/00207454.2020.1720677
大小:4261 kb
页数:15 PAGES
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目录:
  • Abstract
    • Introduction
    • Materials and methods
      • Ethics
      • Gene expression datasets
      • Identification of differentially expressed genes
      • Functional enrichment
      • Network construction of protein–protein interaction
      • Validated the expression levels of DEGs in GSE1297 dataset
      • ROC curve analysis
      • Statistical analysis
    • Results
      • DEGs in AD
      • Dysregulated biological processes in AD brain
      • Dysregulated biological pathways in AD brain
      • Protein–protein interaction network in AD brain
      • The common DEGs in whole blood and AD brain regions
      • The expression levels of common DEGs were analyzed in GSE1297 dataset
      • ROC curve analysis
    • Discussion
    • Conclusion
    • Disclosure statement
    • References

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