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标题:Effects of High Glucose–Induced Lysyl Oxidase Propeptide on Retinal Endothelial Cell Survival
时间:2020-10-14 22:21:35
DOI:10.1016/j.ajpath.2019.06.004
PMID:31537300
大小:1257 kb
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目录:
  • Effects of High Glucose–Induced Lysyl Oxidase Propeptide on Retinal Endothelial Cell Survival
    • Materials and Methods
      • Cell Culture
      • Animals
      • rLOX-PP and PBS Intravitreal Injection
      • WB Analysis
      • Differential Dye Staining
      • Retinal Trypsin Digestion
      • Statistical Analysis
    • Results
      • Effect of HG on LOX-PP and Pro-LOX Expression in RRECs
      • Effects of HG and rLOX-PP on AKT Activity in RRECs
      • Effects of HG and rLOX-PP on Cleaved Caspase-3 Activation in RRECs
      • rLOX-PP Promotes HG-Induced Apoptosis in RRECs
      • Effect of Diabetes on LOX-PP Expression in Rat Retinas
      • rLOX-PP Overexpression Compromises AKT Activation in Rat Retinas
      • rLOX-PP Increases the Number of ACs and PL in Rat Retinas
    • Discussion
    • References

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