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标题:Evaluating antibody monomer separation from associated aggregates using mixed-mode chromatography
时间:2020-09-17 00:17:25
DOI:10.1016/j.chroma.2013.04.018
大小:1667 kb
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目录:
  • Evaluating antibody monomer separation from associated aggregates using mixed-mode chromatography
    • 1 Introduction
    • 2 Materials and methods
      • 2.1 Materials
      • 2.2 Chromatographic methods
      • 2.3 Assays
    • 3 Results and discussion
      • 3.1 mAb aggregates in the elution pool from Protein A capture
      • 3.2 Aggregate removal in flow-through mode with mixed-mode chromatography
      • 3.3 Comparison with traditional resins
    • 4 Conclusions
    • Acknowledgements
    • References

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