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标题:Amitriptyline prevents CPT-11-induced early-onset diarrhea and colonic apoptosis without reducing overall gastrointestinal damage in a rat model of mucositis
时间:2020-09-16 16:34:06
DOI:10.1007/s00520-018-4511-8
大小:2487 kb
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目录:
  • Amitriptyline...
    • Abstract
    • Abstract
    • Abstract
    • Abstract
    • Abstract
    • Introduction
    • Methods
      • Chemicals
      • Animals and ethics
      • Experimental design
      • GI toxicity assessment
      • Histological examination
      • Epithelial apoptosis and proliferation
      • Transcript expression of innate and adaptive immunity in colon
      • TLR2, TLR4, and IL-1β expression
      • Statistical analysis
    • Results
      • GI toxicity
      • Mucosal injury: histological analysis
      • Apoptosis
      • Proliferation
      • PCR array
      • Protein expression of TLR2, TLR4, and IL-1β in the colon
    • Discussion
    • References

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