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标题:New imidazoles cause cellular toxicity by impairing redox balance, mitochondrial membrane potential, and modulation of HIF-1α expression
时间:2020-08-02 10:31:51
DOI:10.1016/j.bbrc.2020.05.059
大小:1207 kb
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目录:
  • New imidazoles cause cellular toxicity by impairing redox balance, mitochondrial membrane potential, and modulation of HIF- ...
    • 1. Introduction
    • 2. Materials and methods
      • 2.1. General
      • 2.2. Imidazole compounds
      • 2.3. The cytotoxicity of imidazoles
      • 2.4. Cellular reactive oxygen species (ROS) measurement
      • 2.5. Mitochondrial membrane potential determination
      • 2.6. Hypoxia-inducing factor 1-alpha (HIF-1α) detection and measurement
      • 2.7. Statistical analysis
    • 3. Results
      • 3.1. Imidazole derivatives
      • 3.2. Cellular toxicity and biochemical mechanisms
    • 4. Discussion
    • Declaration of competing interest
    • Acknowledgments
    • References

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