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标题:Ampelopsin alleviates sevoflurane-induced cognitive dysfunction by mediating NF-κB pathway in aged rats
时间:2020-08-02 02:47:11
DOI:10.1007/s13258-019-00897-5
大小:3517 kb
页数:10 PAGES
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目录:
  • Ampelopsin alleviates sevoflurane-induced cognitive dysfunction by mediating NF-κB pathway in aged rats
    • Abstract
      • Background
      • Purpose
      • Methods
      • Results
      • Conclusion
    • Introduction
    • Materials and methods
      • Animals and ethics
      • Animal grouping and treatment
      • Morris water maze (MWM) test
      • Context fear conditioning (CFC) test
      • Hippocampus tissue preparation
      • Real time PCR
      • Enzyme-linked immunosorbent assays (ELISAs)
      • Measurement of caspase activity
      • Western blot
      • Statistical analysis
    • Results
      • Ampelopsin ameliorated cognitive deficits induced by sevoflurane in aged rats
      • Ampelopsin reduced the levels of cytokines induced by sevoflurane in aged rats
      • Ampelopsin suppressed neural cell apoptosis induced by sevoflurane in aged rats
      • Ampelopsin inhibited the activation of NF-κB pathway induced by sevoflurane in aged rats
    • Discussion
    • Conclusion
    • References

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