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标题:Thienopyrrole-expanded BODIPY as a potential NIR photosensitizer for photodynamic therapy.
时间:2020-01-14 21:37:27
DOI:10.1039/c3cc40746b
PMID:23536148
作者:Yang, Yongchao; Guo, Qiuli; Chen, Huachao
关键词:SINGLET-OXYGEN GENERATION;NEAR-INFRARED FLUORESCENCE;RESTRICTED;AZA-BODIPY;HIGHLY FLUORESCENT;ENERGY-TRANSFER;IN-VITRO;SPECTROSCOPIC;PROPERTIES;BASIC PRINCIPLES
出版源: 《Chemical Communications》 ,49 (38) :3940
摘要:The synthesis and characterization of a highly photostable bromo-substituted BODIPY dye (I) fused-ring-expanded with thienopyrrole moieties is reported. The results of MTT assays and flow cytometric analyses in living HeLa cells demonstrate that I has a high singlet oxygen quantum yield (Phi(Delta) = 0.63) and exhibits photocytotoxicity upon irradiation in the NIR region making it potentially suitable for use in PDT.
大小:1042 kb
页数:12 PAGES
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