在线客服: 点击这里给我发消息  新用户使用步骤:会员注册→充值→重新登入→进入资源
标题:Experimental occlusal interference induces long-term masticatory muscle hyperalgesia in rats.
时间:2019-11-19 21:31:49
DOI:10.1016/j.pain.2009.04.029
PMID:19473767
作者:Ye Cao; Qiu-Fei Xie; Kai Li
关键词:Occlusal interference;Muscle pain;Mechanical hyperalgesia;Central sensitization;Animal model
摘要:http://linkinghub.elsevier.com/retrieve/pii/S0304395909002516
大小:624 kb
下载: 点击下载
预览:

浏览器不支持嵌入PDF阅读,打开新页面在线阅读

目录:
  • Experimental occlusal interference induces long-term masticatory muscle hyperalgesia in rats
    • Introduction
    • Materials and methods
      • Subjects
      • Animal model of occlusal interference
      • Measurement of nociceptive threshold to mechanical pressure of the masticatory muscles
      • Experimental design
        • Nociceptive behavior measurement following CFA injection
        • Nociceptive behavior measurement following experimentally occlusal interference
        • Nociceptive behavior measurement following removal of occlusal interference appliance
        • Nociceptive behavior measurement following systemic MK801 treatment
      • Statistical analysis
    • Results
      • Mechanical hyperalgesia was induced by ipsilateral muscular injection of CFA into the masseter muscle
      • Experimental occlusal interference induced a long-term masticatory muscle hyperalgesia
      • Removal of occlusal interference appliance did not block the mechanical hyperalgesia
      • MK801 reversed the experimental occlusal interference-induced mechanical hyperalgesia
    • Discussion
      • A modification for the tip of von Frey filament
      • Major findings
      • Mechanisms by which occlusal interference leads to chronic pain
      • Masticatory muscle pain models and occlusal alteration models
      • Comparison with clinical findings in human
      • Summary
    • Conflicts of interest
    • Acknowledgement
    • References

本页内容由网络收集而来,版权归原创者所有,如有侵权请及时联系