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标题:Interplay between cholesterol and drug metabolism
时间:2019-11-08 22:45:14
DOI:10.1016/j.bbapap.2010.05.014
大小:802 kb
页数:16 PAGES
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目录:
  • Interplay between cholesterol and drug metabolism
    • Central role of cholesterol in physiological processes
    • Regulation of cholesterol homeostasis
    • Nuclear receptors involved in cholesterol homeostasis and drug metabolism
      • FXR
      • LXR
      • PXR
      • CAR
      • VDR
      • GR
    • Interplay between drugs and cholesterogenic molecules
      • Nuclear receptors in cholesterol and bile acid homeostasis
      • Nuclear receptor cross-talk preventing bile acid toxicity
      • Role of nuclear receptors in regulation of vitamin D metabolism
      • Glucocorticoid regulation of drug-metabolizing P450 enzymes
    • Concluding remarks
    • Acknowledgements
    • References

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