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标题:Role of Ku70 in the apoptosis of inflamed dental pulp stem cells.
时间:2019-10-10 16:41:50
DOI:10.1007/s00011-018-1167-2
PMID:30008029
大小:5029 kb
页数:13 PAGES
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目录:
  • Role of Ku70 in the apoptosis of inflamed dental pulp stem cells
    • Abstract
      • Aim
      • Methods
      • Results
      • Conclusions
    • Introduction
    • Materials and methods
      • Cell cultures
      • Immunohistochemistry
      • Short interfering RNAs and transfection
      • Cell viability
      • Western blotting
      • Immunofluorescent staining
      • Real-time quantitative polymerase chain reaction
      • Terminal deoxynucleotidyl transferase dUTP nick end labeling assay
      • Statistical analysis
    • Results
      • DPSCs with repeated LPS stimulation induced DSB
      • DPSCs with repeated LPS stimulation induced DNA damage response (DDR)
      • Knockdown of Ku70 in DPSCs induced the expression of γ-H2A.X
      • Knockdown of Ku70 decreased cell viability and promoted DPSCs apoptosis
    • Discussion
    • Acknowledgements
    • References

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