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标题:Differential temporal profile of lowered blood glucose levels (3.5 - 6.5 mM versus 5 - 8 mM) in patients with severe traumatic brain injury
时间:2019-10-09 23:08:46
DOI:10.1186/cc6974
大小:467 kb
页数:14 PAGES
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目录:
  • Abstract
    • Introduction
    • Methods
    • Results
    • Conclusion
  • Introduction
  • Materials and methods
    • Propensity-matched patients
    • Inclusion criteria
    • Exclusion criteria
    • Standardized critical care
    • Investigated parameters
    • Statistical analysis
  • Results
    • Demographic data and mortality
    • Influence of additional injuries
    • Changes in blood glucose levels
    • Blood glucose variability
    • Incidences and time points of decreased blood glucose levels
    • Incidences and time points of elevated blood glucose levels
    • Changes in administered insulin and norepinephrine
      • Table 1
    • Changes in intracranial pressure and cerebral perfusion pressure
      • Table 2
      • Table 3
    • Impact of blood glucose diverging from the anticipated blood glucose targets
    • Caloric intake
    • Bacteraemia, urinary tract infection, positive tracheobronchial secretions and blood inflammation parameters
  • Discussion
    • Limitations of this retrospective study
    • Blood glucose and secondary brain damage
    • Pharmacodynamic effects of insulin
    • Control of blood glucose levels
    • Are there different requirements for specific time points following severe TBI?
  • Conclusion
  • Competing interests
  • Authors' contributions
  • Acknowledgements
  • References

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