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标题:Diversity within the JMJD2 histone demethylase family.
时间:2019-08-14 22:21:05
DOI:10.1016/j.bbrc.2006.12.147
PMID:17207460
作者:Shin S;Janknecht R
出版源: 《Biochemical & Biophysical Research Communicati... ,2007 ,353 (4) :973-977
摘要:Diversity within the JMJD2 histone demethylase family.Histone demethylationJmjC domainJMJD2JmjN domainTranscriptionJMJD2A–D belong to the JmjC domain-containing family of histone demethylases. JMJD2D is the most structurally divergent JMJD2 protein as it lacks the PHD and Tudor domains present in JMJD2A–C. Here, we systematically analyzed the histone demethylase specificity...
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目录:
  • Diversity within the JMJD2 histone demethylase family
    • Materials and methods
    • Results
      • Analysis of JMJD2 histone demethylase activity in blank vivo
      • Structure-function analyses
      • Association within the JMJD2 protein family
      • Gene regulation mediated by JMJD2 proteins
    • Discussion
    • References

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