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标题:Melatonin administration prevents cardiac and diaphragmatic mitochondrial oxidative damage in senescence-accelerated mice.
时间:2019-07-16 16:24:02
DOI:10.1677/JOE-07-0260
PMID:17761903
作者:M I Rodriguez;G Escames;L C López;J A García;D Acuña-Castroviejo
出版源: 《Journal of Endocrinology》 ,2007 ,194 (3) :637-643
摘要:Melatonin administration prevents cardiac and diaphragmatic mitochondrial oxidative damage in senescence-accelerated mice.DiaphragmMitochondriaMitochondria, MuscleMitochondria, HeartAnimalsMiceMice, Mutant StrainsAging, PrematureMelatoninGlutathione ReductaseAbstract Cardiac and diaphragmatic mitochondria from male SAMP8 (senescent) and SAMR1 (resistant) mice of 5 or 10 months of age were ...
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目录:
  • Outline placeholder
    • Introduction
    • Materials and Methods
      • Reagents
      • Animals
      • Isolation of mitochondria
      • LPO determination
      • Measurements of GPx and GRd activities
      • Measurement of GSH and GSSG
      • Statistical analysis
    • Results
    • Discussion
    • Acknowledgements
    • References

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