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标题:Melatonin improves inflammation processes in liver of senescence-accelerated prone male mice (SAMP8).
时间:2019-07-16 16:22:07
DOI:10.1016/j.exger.2010.08.016
PMID:20817086
作者:Sara Cuesta;Roman Kireev;Katherine Forman;Cruz García;Germaine Escames
出版源: 《Experimental Gerontology》 ,2010 ,45 (12) :950-956
摘要:Melatonin improves inflammation processes in liver of senescence-accelerated prone male mice (SAMP8)AgingInflammationCytokinesSenescence-accelerated mouseMelatoninAging is associated with an increase in oxidative stress and inflammation. The aim of this study was to investigate the effect of aging on various physiological parameters related to inflammation in livers obtained from two ...
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目录:
  • Melatonin improves inflammation processes in liver of senescence-accelerated prone male mice (SAMP8)
    • Introduction
    • Materials and methods
      • Animals
      • RNA isolation
      • Western blotting analysis
      • Statistical analyses
    • Results
      • Inflammatory TNF-α, IL-1 β and anti-inflammatory IL-10 mRNA and protein expression
      • MCP1 mRNA expression
      • iNOS mRNA expression
      • HO-1 and HO-2 mRNA and protein expression
      • NFκB, NFκB 2 and NKAP mRNA expression
    • Discussion
    • Acknowledgements
    • References

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