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标题:Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase IIIβ
时间:2019-06-13 00:21:45
作者:Florentine U. Rutaganira;Melissa L. Fowler;Jacob A. McPhail;Michael A. Gelman;Khanh Nguyen
出版源: 《Journal of Medicinal Chemistry》 ,2016 ,59 (5) :1830
摘要:Type III phosphatidylinositol 4-kinase (PI4KIIIβ) is an essential enzyme in mediating membrane trafficking and is implicated in a variety of pathogenic processes. It is a key host factor mediating replication of RNA viruses. The design ...
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