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标题:The chronic autoimmune thyroiditis quality of life selenium trial (CATALYST): study protocol for a randomized controlled trial.
时间:2019-06-13 00:17:29
DOI:10.1186/1745-6215-15-115
PMID:24716668
作者:Kristian Hillert Winther;Torquil Watt;Jakob Bue Bjørner;Per Cramon;Ulla Feldt-Rasmussen
出版源: 《Trials》 ,2014 ,15 (1) :115-115
摘要: The chronic autoimmune thyroiditis quality of life selenium trial (CATALYST): study protocol for a randomized controlled trial Kristian Hillert Winther, Torquil Watt, Jakob Bue ...B, Pociot F, Skoog M, Winkel P, Rasmussen AK: Selenium supplementation for patients with Graves’ hyperthyroidism (the GRASS trial): study protocol for a randomized controlled trial....
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目录:
  • Abstract
    • Background
    • Methods/Design
    • Discussion
    • Trial registration
  • Background
  • Methods/design
    • Objectives
    • Design
    • Trial participants
      • Inclusion criteria
      • Exclusion criteria
    • Trial intervention
      • Selenium
      • Placebo
      • The trial data management system (TDMS)
      • Randomization
      • Informed consent procedure
      • Concomitant medication or treatment
      • Monitoring participant adherence to intervention
      • Discontinuation
      • Blinding
    • Safety
    • Outcomes
      • Primary outcome
      • Secondary outcomes
      • Assessment of adverse reactions and events
    • Research biobank
    • Monitoring
    • Statistical analyses
      • Primary outcome: sample size estimation
      • Secondary outcomes: power estimation
      • Serum TPO-Ab concentration
      • LT4 dosage
      • Expected participant recruitment
      • Data analyses
      • Analytical procedures
      • Analytical categories
      • Missing values
    • Ethical considerations
  • Discussion
  • Trial status
  • Abbreviations
  • Competing interests
  • Authors’ contributions
  • Acknowledgements
  • Author details
  • References

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