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标题:Evaluation of healing activity of PVA/chitosan hydrogels on deep second degree burn: pharmacological and toxicological tests.
时间:2019-06-12 17:15:46
DOI:10.1016/j.burns.2012.05.021
PMID:22738824
作者:Assia Nacer Khodja;Mohamed Mahlous;Djamel Tahtat;Samah Benamer;Souad Larbi Youcef
出版源: 《Burns Journal of the International Society for... ,2013 ,39 (1) :98-104
摘要:Khodia A.N., Mahlous M., Tahtat D., Benamer S., Youcef SL., Chader H., Mouhoub L., Sedgelmaci M., Ammi N., Mansouri MB., Mameri S; (2013) Evaluation of healing activity of PVA/chitosan hydrogels on deep second degree burn: pharmacological and toxicological tests. Burns 39, 98-104, DOI: 10.1016/j.burns.2012.05.021...
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目录:
  • Evaluation of healing activity of PVA/chitosan hydrogels on deep second degree burn: Pharmacological and toxicological tests
    • 1 Introduction
    • 2 Materials and methods
      • 2.1 Materials
      • 2.2 Preparation of hydrogel
      • 2.3 Pharmacological test
        • 2.3.1 Animals
        • 2.3.2 Creation of a burn wound model
      • 2.4 Toxicological test
        • 2.4.1 Test of skin irritation
        • 2.4.2 Test of mucosal membranes irritation
      • 2.5 Histological analysis
      • 2.6 Statistical analysis
    • 3 Results and discussion
      • 3.1 Pharmacological test
      • 3.2 Wound healing test
        • 3.2.1 Between Day 0 and Day 2 (after scab removing)
        • 3.2.2 Between Day 2 and Day 6
        • 3.2.3 Between Day 6 and Day 9
      • 3.3 Toxicological test
        • 3.3.1 Test of skin irritation and mucosal membranes irritation
      • 3.4 Histological analysis
    • 4 Conclusion
    • Conflict of interest
    • Acknowledgement
    • References

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