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标题:Drug metabolism by Escherichia coli expressing human cytochromes P450.
时间:2019-06-12 17:06:32
DOI:10.1038/nbt0897-784
PMID:9255795
作者:Asit Parikh;Elizabeth M.J. Gillam;F. Peter Guengerich
出版源: 《Nature Biotechnology》 ,1997 ,15 (8) :784
摘要:Drug metabolism by Escherichia coli expressing human cytochromes P450drug metabolismcytochrome P450NADPH-cytochrome P450bicistronic constructsReductasePurificationRat4-HydroxylationOxidoreductaseHydroxylationThe broad substrate specificity of the cytochrome P450 (P450) enzyme superfamily of heme-thiolate proteins lends itself to diverse environmental and pharmaceutical applications. Until recently, ...
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