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标题:ZAP70: a master regulator of adaptive immunity.
时间:2019-05-15 23:00:29
DOI:10.1007/s00281-010-0196-x
PMID:20135127
作者:Alain Fischer;Capucine Picard;Karine Chemin;Stéphanie Dogniaux;Françoise le Deist
出版源: 《Seminars in Immunopathology》 ,2010 ,32 (2) :107-116
摘要:The protein tyrosine kinase ZAP70 became the subject of intense scrutiny in the early nineties, when ZAP70 mutations were characterized in several young pa...
大小:301 kb
页数:11 PAGES
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目录:
  • ZAP70: a master regulator of adaptive immunity
    • Abstract
    • Structure of the ZAP70 protein
    • Signalling pathways controlled by ZAP70 in T cells
    • Signalling pathways controlled by ZAP70 in B cells
    • ZAP70 and autoimmunity in mice and humans
    • ZAP70 and primary immunodeficiencies
    • Conclusions
    • References

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