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标题:A theoretical validation of the substrate depletion approach to determining kinetic parameters.
时间:2019-03-15 12:16:35
DOI:10.1124/dmd.106.010777
PMID:16751261
作者:Nath A;Atkins WM
出版源: 《Drug Metabolism & Disposition the Biological F... ,2006 ,34 (9) :1433
摘要:The substrate depletion approach is an increasingly popular alternative to the traditional method (observing product formation) of determining the kinetic parameters (KM and Vmax) of an enzyme. Obach and Reed-Hagen (Drug Metab Dispos 30:...
大小:261 kb
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