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标题:Single-cell metabolomics: analytical and biological perspectives.
时间:2019-02-11 23:03:32
DOI:10.1126/science.1243259
PMID:24311695
作者:R. Zenobi
出版源: 《Science》 ,2013 ,342 (6163) :1201
摘要:Particularly interesting fields of application are cancer biology, stem cell research, and monitoring of xenobiotics and drugs in tissue sections at the single-cell level.doi:10.1126/science.1243259R. Zenobi《Science》R. Zenobi, Single-cell metabolomics: analytical and biological perspectives, Science 342 (6163) (2013)....
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目录:
  • Single-Cell Metabolomics: Analytical and Biological Perspectives
    • General Considerations for Single-Cell Metabolomics
    • Preparing Single-Cell Samples for Analysis
      • Microfluidics
      • Nanoscale Devices
    • Analytical Methodologies for Identifying Metabolites in Single Cells
      • Mass Spectrometry
      • Mass Spectrometry Imaging
      • Fluorescence-Based Detection, Fluorescence Biosensors, and FRET Biosensors
      • Vibrational Spectroscopy
      • Separation-Based Chemical Analyses
    • Discussion and Outlook
    • References and Notes

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