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标题:Tissue- and site-specific DNA recombination in transgenic mice
时间:2019-02-11 16:51:29
DOI:10.1073/pnas.89.15.6861
作者:P C Orban;D Chui;J D Marth
出版源: 《Proceedings of the National Academy of Science... ,1992 ,89 (15) :6861-6865
摘要:MATERIALS AND METHODS Transgene Construction and Transgenic Mouse Production. The Cre transgene expression vector was constructed by inserting the 1.5-kilobase (kb) Xho I-Xba I fragment ...Evidence for the predicted Cre-mediated recombination structure was obtained by using a loxP- specific DNA probe (Fig. 2C). Hybridization was observed to a novel 1.60-kb Stu I-...
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