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标题:Effect of cobalt and chromium ions on bcl-2, bax, caspase-3, and caspase-8 expression in human U937 macrophages
时间:2019-01-11 10:39:16
DOI:10.1016/j.biomaterials.2003.08.040
作者:Petit A;Mwale F;Zukor DJ;Catelas I;Antoniou J
出版源: 《Biomaterials》 ,2004 ,25 (11) :2013-2018
摘要:Effect of cobalt and chromium ions on bcl-2, bax, caspase-3, and caspase-8 expression in human U937 macrophages.Hip replacementProsthesisMacrophageMetal ionsThe bcl-2 and caspase families of proteins play a central role in the modulation of apoptosis. The purpose of this study was to analyze the effect of Co and Cr ions on the expression of bcl-2, bax, caspase...
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目录:
  • Effect of cobalt and chromium ions on bcl-2, bax, caspase-3, and caspase-8 expression in human U937 macrophages
    • Introduction
    • Materials and methods
      • Cell culture
      • Protein expression
      • Caspase activity
      • Statistical analysis
    • Results
      • Expression of bcl-2 and bax
      • Expression of caspase-3 and caspase-8 active fragments
      • Activity of caspase-3 and caspase-8
    • Discussion
    • Acknowledgements
    • References

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