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标题:Influence of hyperoxia and mechanical ventilation in lung inflammation and diaphragm function in aged versus adult rats.
时间:2018-12-07 00:03:25
DOI:10.1007/s10753-013-9762-4
PMID:24158570
作者:P. V. Andrade;J. M. dos Santos;H. C. A. Silva;D. D. Wilbert;S. S. Cavassani
出版源: 《Inflammation》 ,2014 ,37 (2) :486-494
摘要:Influence of Hyperoxia and Mechanical Ventilation in Lung Inflammation and Diaphragm Function in Aged Versus Adult RatsAnimalsRatsRats, WistarDiaphragmLungBronchoalveolar Lavage FluidMalondialdehydeDisease Models, AnimalHyperoxiaInflammation MediatorsAlthough assist ventilation with FIO2 0.21 is the preferable mode of ventilation in the intensive care unit, sometimes controlled ventilation ...
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页数:10 PAGES
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目录:
  • Influence of Hyperoxia and Mechanical Ventilation in Lung Inflammation and Diaphragm Function in Aged Versus Adult Rats
    • Abstract
    • INTRODUCTION
    • MATERIALS AND METHODS
      • Experimental Animals and Study Design
      • Protocol for MV-Treated Animals
      • Measurements
        • Arterial Blood Gas analysis
        • Bronchoalveolar Lavage (BAL)
        • Total Protein Lung Content
        • Cytokine Assay in BAL
        • Measurement of Lipid Derived Oxidation Products, Malondialdehyde (MDA)
        • Measurement of Contractile Function
        • Test of Tetanic Stimulation (Tetanic Peak Force — Po)
        • Test with Caffeine
        • Morphology
      • Statistical Analysis
    • RESULTS
      • Arterial Blood Gas Analysis
      • Protein Leakage in BAL
      • MDA Measurement in the Lung
      • Cytokine Concentrations in BAL
      • Measurement of Isometric Contractile Property
      • Morphology
    • DISCUSSION
      • References

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