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标题:Hepatic cytochrome P450 degradation: mechanistic diversity of the cellular sanitation brigade.
时间:2018-12-06 22:44:54
DOI:10.1081/DMR-120023683
PMID:12959413
作者:Correia MA
出版源: 《Drug Metabolism Reviews》 ,2003 ,35 (2-3) :107-143
摘要:Hepatic cytochrome P450 degradation: mechanistic diversity of the cellular sanitation brigade.ER (Endoplasmic reticulumERADP450 degradationER degradationProteasomeUbiquitinHepatic cytochromes P450 (P450s) are monotopic endoplasmic reticulum (ER)-anchored hemoproteins that exhibit heterogenous physiological protein turnover. The molecular/cellular basis for such heterogeneity is not well ...
大小:587 kb
页数:38 PAGES
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